The pre-T-cell receptor is a protein receptor produced by developing T lymphocytes at the pre-T-cell stage, composed of TCRβ chains, a surrogate α chain (pTα), and CD3 signaling chains; its signaling induces proliferation, CD4/CD8 expression, and cessation of TCRβ chain rearrangement.
El receptor pre-T es un receptor proteico producido por linfocitos T en desarrollo en la etapa pre-T, compuesto por cadenas TCRβ, una cadena α sustituta (pTα) y cadenas de señalización CD3; su señalización induce proliferación, expresión de CD4/CD8 y cese de la reorganización de la cadena TCRβ.
| Front | Receptor protein produced by developing Treglymphocytes at the pre-T-cell stage. It is composed of TCRβ chains that pair with a surrogate α chain called pTα pre-T-cell α, and is associated with the CD3 signaling chains. Signaling through this receptor induces pre-T-cell proliferation, expression of CD4 and CD8, and cessation of TCR β chain rearrangement |
|---|---|
| Back | pre-T-cell receptor |
Learn with these flashcards. Click next, previous, or up to navigate to more flashcards for this subject.
Next card: Cells stage b-lymphocyte development displayed b-cell surface marker
Previous card: Receptor cell pre-b proteins signaling rag produced includes
Up to card list: Janeway's Immunobiology 9th Edition Concept Flash Card