The pre-B-cell receptor is a receptor produced by pre-B cells, comprising an immunoglobulin heavy chain, surrogate light-chain proteins, and Igα and Igβ signaling subunits; its signaling induces cell cycle entry, cessation of RAG gene expression, and cell expansion.
El receptor pre-B es un receptor producido por las células pre-B, compuesto por una cadena pesada de inmunoglobulina, subunidades de señalización Igα e Igβ y proteínas de cadena ligera sustitutas; su señalización induce la entrada de la célula pre-B en el ciclo celular, la detención de la expresión de genes RAG y la expansión celular.
| Front | Receptor produced by pre-B cells that includes an immunoglobulin heavy chain, as well as surrogate light-chain proteins, Igα and Igβ signaling subnits. Signaling through this receptor induces the pre-B cell to enter the cell cycle, to turn off the RAG genes, to degrade the RAG proteins, and to expand by several cell divisions |
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| Back | pre-B-cell receptor |
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