The B-cell receptor (BCR) is a cell-surface receptor on B cells that recognizes specific antigens. It's made of a transmembrane immunoglobulin that binds antigen, along with Igα and Igβ chains for signaling, and upon activation, B cells become plasma cells that produce antibodies with the same antigen specificity.
O receptor de superfície celular nos linfócitos B para antígeno específico. É composto por uma molécula de imunoglobulina transmembranar que reconhece antígeno associado às cadeias invariantes Igα e Igβ que têm função de sinalização. Após ativação por antígeno, os linfócitos B se diferenciam em plasmócitos produtores de moléculas de anticorpos com a mesma especificidade de antígeno que este receptor.
| Front | The cell-surface receptor on B cells for specific antigen. It is composed of a transmembrane immunoglobulin molecule which recognizes antigen associated with the invariant Igα and Igβ chains which have a signaling function. On activation by antigen, B cells differentiate into plasma cells producing antibody molecules of the same antigen specificity as this receptor |
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| Back | B-cell antigen receptor, B-cell receptor BCR |
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