This flashcard defines bone marrow as the primary site of blood cell generation from hematopoietic stem cells, also involved in B-cell development and Treg cell precursor origin. Transplanting it can restore all blood cell components, crucial for adaptive immunity.
El tejido donde se generan inicialmente todos los elementos celulares de la sangre —glóbulos rojos, glóbulos blancos y plaquetas— a partir de células madre hematopoyéticas. Este tejido es también el sitio del desarrollo posterior de las células B en mamíferos y la fuente de células madre que dan lugar a las células Treg tras la migración al timo. Por lo tanto, el trasplante de este tejido puede restaurar todos los elementos celulares de la sangre, incluidas las células necesarias para las respuestas inmunitarias adaptativas.
| Front | The tissue where all the cellular elements of the blood—red blood cells, white blood cells, and platelets—are initially generated from hematopoietic stem cells. This tissue is also the site of further B-cell development in mammals and the source of stem cells that give rise to Tregcells on migration to the thymus. Thus, transplantation of this tissue can restore all the cellular elements of the blood, including the cells required for adaptive immune responses |
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| Back | bone marrow |
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