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Signaling Polyubiquitin Chains Covalent Ligation Lysine Amino Group

Front In polyubiquitin chains, the covalent ligation of lysine 63 amino group of one ubiquitin protein with the carboxy terminus of a second ubiquitin. This type of linkage is most associated with activation of signaling by formation of a scaffold recognized by signaling adaptors such as TAB1/2
Back K63-linkages

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