K63-linkages are the covalent ligation of lysine 63 amino group of one ubiquitin protein with the carboxy terminus of a second ubiquitin in polyubiquitin chains. This type of linkage is most associated with activation of signaling by formation of a scaffold recognized by signaling adaptors such as TAB1/2.
Las enlaces K63 son la ligación covalente del grupo amino lisina 63 de una proteína ubiquitina con el extremo carboxilo de una segunda ubiquitina en las cadenas de poliubiquitina. Este tipo de enlace se asocia principalmente con la activación de la señalización por formación de un andamio reconocido por proteínas adaptadoras de señalización como TAB1/2.
| Front | In polyubiquitin chains, the covalent ligation of lysine 63 amino group of one ubiquitin protein with the carboxy terminus of a second ubiquitin. This type of linkage is most associated with activation of signaling by formation of a scaffold recognized by signaling adaptors such as TAB1/2 |
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| Back | K63-linkages |
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