Immunoreceptor tyrosine-based activation motif (ITAM) are sequence motifs in the signaling chains of receptors, such as antigen receptors on lymphocytes, that are the site of tyrosine phosphorylation after receptor activation, leading to recruitment of other signaling proteins.
El motivo de activación de tirosina basado en inmunoreceptores (ITAM) son motivos de secuenciación en las cadenas de señalización de receptores, como los receptores de antígenos en linfocitos, que son el sitio de fosforilación de tirosina tras la activación del receptor, lo que lleva al reclutamiento de otras proteínas de señalización.
| Front | Sequence motifs in the signaling chains of receptors, such as antigen receptors on lymphocytes, that are the site of tyrosine phosphorylation after receptor activation, leading to recruitment of other signaling proteins |
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| Back | immunoreceptor tyrosine-based activation motif ITAM |
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