The 12/23 rule is a phenomenon in immunoglobulin and T-cell receptor gene rearrangement where two gene segments can only be joined if their flanking recombination signal sequences have spacers of 12 and 23 base pairs, respectively.
Phenomenon wherein two gene segments of an immunoglobulin or T-cell receptor can be joined only if one recognition signal sequence has a 12-base-pair spacer and the other has a 23-base-pair spacer
| Front | Phenomenon wherein two gene segments of an immunoglobulin or T-cell receptor can be joined only if one recognition signal sequence has a 12-base-pair spacer and the other has a 23-base-pair spacer |
|---|---|
| Back | 12/23 rule |
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