Tumor rejection antigens (TRAs) are antigens on the surface of tumor cells recognized by T cells, leading to tumor cell attack; TRAs are peptides of mutant or overexpressed cellular proteins bound to MHC class I molecules on the tumor-cell surface.
Tumor rejectie antigenen (TRAs) zijn antigenen op het oppervlak van tumorcellen die door T-cellen kunnen worden herkend, wat leidt tot een aanval op de tumorcellen. TRAs zijn peptiden van gemuteerde of overmatige cellulaire eiwitten gebonden aan MHC klasse I moleculen op het tumorceloppervlak.
| Front | Antigens on the surface of tumor cells that can be recognized by T cells, leading to attack on the tumor cells. TRAs are peptides of mutant or overexpressed cellular proteins bound to MHC class I molecules on the tumor-cell surface |
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| Back | tumor rejection antigens |
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