Question

Helicobacter Pylori pathogenesis

Accepted Answer

Drills into mucous layer of gut  attach to cell  produces urease = degrades urea from stomach producing ammonia and CO2- Doesn’t invade tissue - Ammonia causes: > Toxic to cells and leads to epithelium damage> Buffer acidity to help bacteria survive

Front	Helicobacter Pylori pathogenesis
Back	Drills into mucous layer of gut  attach to cell  produces urease = degrades urea from stomach producing ammonia and CO2 - Doesn’t invade tissue - Ammonia causes: > Toxic to cells and leads to epithelium damage > Buffer acidity to help bacteria survive

Ammonia Helicobacter Pylori Pathogenesis Drills Mucous Layer Gut