Helicobacter Pylori colonizes the gastric mucosa by drilling into the mucous layer and producing urease, which neutralizes stomach acidity and causes cell damage.
Helicobacter Pylori, mukus tabakasına girerek ve üreaz üreterek mide asiditesini nötralize edip hücre hasarına neden olarak mide mukozasını kolonize eder.
| Front | Helicobacter Pylori pathogenesis |
|---|---|
| Back | Drills into mucous layer of gut attach to cell produces urease = degrades urea from stomach producing ammonia and CO2 - Doesn’t invade tissue - Ammonia causes: > Toxic to cells and leads to epithelium damage > Buffer acidity to help bacteria survive |
Tags: gram_neg
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