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Enzyme Cells Scids Symptoms Treatment Severe Combined Immunodeficiency

SCIDS (Severe Combined Immunodeficiency Syndrome) occurs because children lack the enzyme ADA, crucial for T and B cell maturation, leading to life-threatening infections. Treatment involves infecting bone marrow stem cells with a retrovirus carrying the normal gene for ADA and returning them to the patient.

SCIDS: Kinder fehlt ein Enzym ADA (Adenosindeaminase), das an der *Reifung* von T- und B-Zellen beteiligt ist. Risiko lebensbedrohlicher Infektionen. Knochenmarkstammzellen werden aus dem Blut entfernt und mit einem *Retrovirus* (RNA) infiziert, das ein normales Gen für das Enzym trägt, und die Zellen werden dem Patienten zurückgegeben.

Front SCIDS
cause
symptoms
treatment
Back Severe Combined Immunodeficiency Syndrome

Children lack an enzyme ADA (Adenosine Deaminase) that is involved in the *maturation* of T and B cells

Risk of life threatening infections

*Bone marrow stem cells* are removed from the blood and infected with a *retrovirus* (RNA) that carries a normal gene for the enzyme and the cells are returned to the patient

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