Cystic fibrosis is caused by a missing gene for a chloride ion transporter, often leading to fatal respiratory infections. Liposomes coated with the required gene are sprayed into the nostrils, but this method has not yet been successful due to limited gene transfer.
Mukoviszidose: Es fehlt das Gen, das für den Transmembrantransporter für Chloridionen kodiert. Patienten sterben oft an Atemwegsinfektionen. *Liposomen* werden mit dem benötigten Gen beschichtet und die Lösung wird in die Nasenlöcher des Patienten gesprüht. Aufgrund der begrenzten Gentransfers ist diese Methode noch nicht erfolgreich.
| Front | Cystic fibrosis cause symptoms treatment success |
|---|---|
| Back | The gene that codes for trans-membrane carrier of chloride ion is missing. Patients often die due to respiratory tract infections *Liposomes* (microscopic vesicles that spontaneously form when lipoproteins are put into a solution) are coated with the required gene and the solution is sprayed into the patient's nostrils. Due to limited gene transfer, this method has not yet been successful. |
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