End-product inhibition occurs when the product of a reaction inhibits the enzyme that produced it, like ATP inhibiting PFK in glucose breakdown to regulate ATP production.
End-product inhibition occurs when the product of a reaction inhibits the enzyme that produced it, like ATP inhibiting PFK in glucose breakdown to regulate ATP production.
| Front | End product inhibition and example 2.1.4(f) |
|---|---|
| Back | - where products of reaction acts as inhibitor to enzyme that produces it - respiration produces ATP via multi step reaction pathway to breakdown glucose - begins with addition of 2 PO4 groups, which breakdown glucose, and is catalysed by PFK enzyme - when increases levels of ATP, it binds on allosteric site of PFK and so glucose broken slower (less ATP produced) - when lower levels, less bound to PFK so glucose broken down faster (more ATP) |
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