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Messenger Triggers Camp Membrane Glucose Action Adrenaline Model

Adrenaline acts as a first messenger, activating adenylyl cyclase which converts ATP to cAMP (a second messenger), triggering glycogenolysis to increase blood glucose.

A adrenalina atua como primeiro mensageiro, ativando a adenilil ciclase, que converte ATP em cAMP (segundo mensageiro), desencadeando a glicogenólise para aumentar a glicose no sangue.

Front action of adrenaline (second messenger model), what does it result in?. messengers
Back
  • triggers liver cells (hydrophilic hormone, so binds with receptors on membrane and triggers chain reaction within cell) to undergo glycogenolysis to increase blood glucose levels for more respiration and muscle contraction
  • once bound, adenylyl cyclase activated (enzyme) which triggers conversion of ATP into cAMP on inner surface of membrane in cytoplasm, cAMP activates protein kinases (enzymes) which phosphorylate (and so activate) other enzymes (which break down glycogen into glucose here)
  • In model, hormone (adrenaline here) is first messenger and cAMP second messenger

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