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Animals Human Gm Pharming Ethical Issues Swine Form

Front GM animals; example, pharming and ethical issues
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  • swine fever-resistent pigs (immune to african swine fever)
  • Pharming (GE animals to form human medicines)
    • creating animal models (addition/removal of genes so animals develop certain diseases to model for development of new therapies)
    • creating human proteins (human gene placed in GM of fertalised animal egg (e.g cow) with a promoter sequence so gene only expressed in mammary glands, fertallised transgenic female embryo returns to mother, and once born, matures and gives birth, it forms milk (with desired human protein), bacteria used sometimes, but cant form all proteins made by eukaryotes
  • Ethical issues
    • using GE animals to model human disease
    • putting human genes in animals
    • welfare compramised while forming GE animals

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