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Blood Basement Membrane Glomerulus Make Plasma Lpp Capsule

Ultrafiltration occurs in the glomerulus under high hydrostatic pressure, forcing fluid through a filtration membrane into Bowman's capsule, resulting in an ultrafiltrate free of cells or large proteins.

A ultrafiltração ocorre no glomérulo sob alta pressão hidrostática, forçando o fluido através de uma membrana de filtração na cápsula de Bowman, resultando em um ultrafiltrado sem células ou proteínas grandes.

Front ultrafilteration
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  • glomerulus supplied with blood by wide afferent (incoming) arteriole from renal artery, and leaves through narrow efferent (outgoing) arteriole, so glomerulus under high hydrostatic pressure, which means blood forced out of walls, then fluid passes through basement membrane (Both make up first sieve), most plasma conents pass basement membrane but blood cells and LPP dont.
  • wall of bowmans capsule involves podocytes that wrap around the capillaries, forming slits to make sure any cells, platelets or LPP that have managed to get through basement membrane dont go through tubule, the filtrate entering capsule contains glucose, salt, urea and other substances in same concs as in plasma, but Ultrafiltrate is less concentrated than the blood plasma



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