Pathology 5&6 - Inflammation

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• Define inflammation complex interaction chemical mediators cells occurs
• Purpose inflammation eliminate injury repair damaged tissue
• Inflammation infection does always mean
• Nonspecific inflammation specific response initially
• Immune inflammation stimulates type response acquired specific limits
• Inflammatory main constituents response vascular endothelial cells mediators
• System blood vascular cells inflammatory body key inflammation
• Type leukocytes present site injury provide information insight
• Cell type predominant tissues inflammation macrophage sits surveys
• Macrophage identify infection inflammation damps pamps activate
• Macrophages cells activated stimulate types begin destroying threat
• Activated macrophages release proinflammatory cytokines list examples il-1
• Endothelial activated macrophages release lipid mediators effect membranes
• Activated macrophages release chemokines perform role attract blood
• Blood flow vasodilation slowing results clinical signs inflammation
• Increased vascular permeability due inflammation results clinical sign
• Activated mast cells release vasoactive substances histamine serotonin
• Cells macrophages mast synthesize types arachidonic pathway leukotrienes
• Increase products arachadonic pathway result functions vascular permeability
• Expression cell adhesion molecules p selectins/glycoproteins vessel wall
• Chemokines aid function leukocytes macrophages release affected tissue
• Plasma derived mediators inflammation acute phase proteins apps
• Albumin concentration inflammation apps describe characteristics  decreases present
• Common kinin bradykinin mediates pain sustains vascular dilation
• Tissue cells respond acutely threat mast macrophages resident
• Blood cells respond acutely inflammation leukocytes neutrophils monocytes
• Cell lives blood responds acute inflammation neutrophils
• Blood neutrophils release bone presence animal clear inflammatory
• Increase neutrophils circulating blood called neutrophilia
• Neutrophils pool blood circulating they?  centre vessel float
• Neutrophils left shift acute cellular response inflammation shifting
• Band neutrophil immature lives bone marrow maturation
• Cbc lots neutrophils increased band cells left shift
• Neutrophils acute inflammation severe rapidly consumed site injury
• Respond wbc's inflammation due allergy parasite eosinophils aggressively
• Eosiniphilia eosinophils present blood increased numbers
• Monocytosis monocytes inflammation increased numbers blood big picture
• Leukocytosis clinical test increase wbc's cbc
• Blood make smears microscope double check analyzer telling
• Rank wbcs present blood highest number lowest neutrophils
• Absolute percentage estimates cbc numbers
• Main goal neutrophils long survive tissues phagocytize foreign
• Site wbc neutrophils call injury attract monocytes stimulation
• Monocytes enter tissue called macrophages
• Inflammatory neutrophils generate mediators response types kinins leukotrienes
• Eosinophils excellent activating type cells mast
• Long eosinophils survive tissue?  days weeks
• Monocytes migrate blood injured tissue neutrophils macrophages long
• Inflammation persists wbc predominant cell type site monocytes
• Cases hard digest foreign material chronic infection type
• Presenting dendritic cells long processes reach tissue main
• Ways classify inflammation acute chronic responding cell type
• Names neutrophilic inflammation suppurative purulent pus
• Neutriphilic inflammation bacterial infectious trauma immune-mediated non-infectious
• Eosinophilic inflammation parasitic i allergy paraneoplastic ni
• Wbcs respond acute inflammation neutrophils eosinphils
• Inflammation chronic pyogranulomatous type cells site caused fungal
• Type wbcs present chronic granulomatous inflammation macrophages multinucleated
• Infectious granulomatous inflammation fungal atypical bacteria foreign body 
• Lymphycytic/plasmacytic inflammation involves type wbc lymphocytes plasma cells
• Infectious agents lymphocytes attack viral antigenic stimulation i
• Ectasis dilated
• Ecto outside
• Micro small
• Mono single
• Morph form
• Myi fly
• Myo muscle
• Myelo marrow
• Pro before
• Proct anus
• Proto first
• Psalter book
• Pseudo false
• Psor itch
• Sub under
• Super over
• Supra above
• Sym together
• Syn together
• Syringo pipe
• Tachy rapid
• Tact touch
• Taen ribbon
• Ov(i egg
• Tapet carpet
• Tel end far
• Tenui thin
• Terato monster
• Tetra four
• Thalam chamber
• Duct convey
• Dys bad ill
• An without not
• Ab from
• Acro extremity
• Ad to
• Adeno gland
• Adipo fat
• Ala-i wing
• Alb-i white
• Algia pain
• Ambi both
• Amphi both
• Amyl starch
• An without not
• Ana up
• Ankylo bent
• Ante before
• Anti against
• Aqua water
• Archi first
• Arthro joint
• Ase enzyme
• Auto self
• Bi two
• Bio life
• Blast germ bud
• Bothri pit
• Brachi arm
• Brady slow
• Caec blind
• Capit head
• Card heart
• Cata down
• Cer horn
• Cervix neck
• Chlor green
• Choan funnel
• Chrom color
• Chyl juice
• Chym juice
• Clast break to
• Coel hollow
• Collum neck
• Conch shell
• Corn horn
• Cortico bark
• Cruci cross
• Crypt hidden
• Cten comb
• Cyan dark blue
• Cyn dog
• Cyt cell hollow
• De down from
• Dent tooth
• Derma skin
• Di double
• Diplo double
• Dis down from
• Duo two
• Dura hard
• Ella,us diminutive
• Emia blood
• Endo within
• Ento within
• Entero intestine
• Erythro red
• Ex out
• Extra beyond
• Fenestra window
• Fer carry bear to
• Flav yellow
• Fug(s flee
• Gamo marriage
• Gastro stomach
• Gen produce to
• Glia glue
• Glossi tongue
• Glyco sweet sugar
• Gnath jaw
• Gogue leading
• Gon angle seed
• Graph write to
• Haemo blood
• Hemi half
• Hepta liver
• Hetero different
• Hex six
• Hippo horse
• Histo tissue
• Homo same
• Horm excite to
• Hyalo glassy clear
• Hydro water
• Hymen membrane
• In not without
• In-en into
• Inter between
• Intra within
• Iso equal
• Itis inflammation
• Lact milk
• Lacun pit lake
• Lamin layer plate
• Leio smooth
• Lepto thin
• Leuco white
• Lemma skin
• Lingua tongue
• Lipo fat
• Lith stone
• Logy discourse
• Lysis divide destroy
• Macro large
• Macula spot
• Mal bad ill
• Mas breast
• Medi middle
• Mega large
• Mes middle
• Meta change beyond
• Meter measure
• Myxo mucus slime
• Necro dead
• Nemo thread
• Neo new
• Nephro kidney
• Neuro nerve
• Nid nest
• Nigr black
• Noct night
• Noto back
• Nucleus nut
• Nud naked
• Nyssus prick to
• Oct eight
• Odont tooth
• Oid like
• Olig few
• Oma tumor
• Omma eye
• Ophalo navel
• Oneh barb
• Oo egg
• Opercul cover a
• Ophthalm eye
• Opisth behind
• Os mouth or
• Orchi testicle
• Ortho straight
• Ose sugar
• Ossi bone
• Osteo bone
• Osti door
• Ot(o ear
• Oxy sharp
• Pachy thick
• Palaeo ancient
• Pan all
• Par beget to
• Para beside
• Pariet wall
• Ped foot
• Penta five
• Peri around
• Phago eat to
• Phil loving
• Phlebo vein
• Phon voice sound
• Phot light
• Phyll leaf
• Phyto plant
• Pia tender
• Plasm formed
• Platy flat
• Pleo more
• Pleuro side
• Pneumon air
• Pod(i-o foot
• Poly many
• Pons bridge
• Porta gate
• Post after
• Pre before
• Psych breath soul
• Psyll flea
• Ptero wing
• Ptyl saliva
• Pulic flea
• Pulmo lung
• Pupa baby
• Pyl gate
• Pyo pus
• Pyri pear
• Quadr spine
• Ram(i branch
• Re again
• Rect straight
• Ren-(i kidney
• Ret-(a-i net
• Rhabdo rod a
• Rheo flow to
• Rhino nose
• Rhyncho snout
• Rhizo root
• Rostri beak
• Rumin throat
• Sagitta arrow
• Salpi trumpet
• Sarco flesh
• Sapro putrid
• Scalar ladder
• Schizo cleft
• Sclera hard
• Scoli bend
• Scope see
• Scut shield a
• Seb tallow
• Sect cut to
• Sella saddle
• Semi half
• Sept wall a
• Septic putrid
• Seti bristle
• Sialo saliva
• Siphon tube
• Siphuncal small tube
• Soma body
• Somn sleep
• Spheno wedge
• Splancho viscera
• Squam scale
• Stat standing
• Stell star
• Steno narrow
• Stereo solid
• Sterco dung feces
• Stetho breast
• Stigmo point
• Stoma mouth
• Strati layered
• Strepto turned
• Stria furrowed
• Strongylo round
• Stylo column
• Theco case covering
• Theli nipple
• Therio beast
• Thermo heat
• Thromb clot
• Thyro door shield
• Thysan fringe
• Tok birth
• Tomo cut to
• Toxo poison
• Trabecul small bean a
• Tracheo windpipe
• Trachy rough
• Tremat hole
• Tri three
• Tricho hair
• Troch pulley
• Trombid timid
• Trop turning
• Trophy nutrition
• Trypano auger an
• Tumor swelling
• Tunic garmet a
• Tympano drum a
• Tryo cheese
• Ultra beyond
• Unci hook
• Uni one
• Uro urine
• Vaso vesseal
• Ven vein
• Ventr belly
• Vermi worm
• Vesicul blister
• Via way
• Villi shaggy
• Vita life
• Vitr glassy
• Vivi alive
• Vora devour to
• Xantho yellow
• Xero dry
• Xylon wood
• Zoo life animal
• Zygo yoke
• Zym ferment

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